Antonio Conte makes two changes to the Tottenham team that lost at home to Liverpool in their last Premier League game.
Fit-again Richarlison and Dejan Kulusevski both return, replacing Yves Bissouma and the injured Ryan Sessegnon.
Tottenham XI: Lloris, Emerson Royal, Dier, Lenglet, Davies, Kulusevski, Bentancur, Hojbjerg, Richarlison, Kane, Perisic
Subs: Forster, Doherty, Skipp, Sanchez, Gil, Spence, Tanganga, Moura, Bissouma
Wilfried Gnonto comes in for the injured Jack Harrison in Leeds’ only change to the side that beat Bournemouth last weekend.
The visitors remain without Patrick Bamford and Mateusz Klich.
Leeds XI: Meslier, Kristensen, Koch, Cooper, Struijk, Adams, Roca, Aaronson, Summerville, Rodrigo, Gnonto
Subs: Robles, Ayling, Firpo, Llorente, Perkins, Gyabi, Gelhardt, Greenwood, Joseph