Klopp had been hopeful that Van Dijk’s condition could see him return quickly speaking after the defeat in London.
“Virgil felt a little bit his muscle, but he said he’s fine and he’s a very good judge of these things.
“I didn’t want to take any risk. The physios looked quite happy when I said I didn’t want to take a risk. It’s not an injury, he just felt the intensity.”
Matip, who replaced Van Dijk on Monday night when the Reds were already 2-0 down, is now likely to come into the team to partner Ibrahima Konate in the back four, with Joe Gomez also an option